Triggered release in lipid bilayer-capped mesoporous silica nanoparticles containing SPION using an alternating magnetic field

Triggered release in lipid bilayer-capped mesoporous silica nanoparticles containing SPION using an alternating magnetic field.

We report here the on-command cargo controlled delivery using an alternating magnetic field (AMF) from magnetic silica mesoporous supports capped with a lipid bilayer.

Glucose-triggered release using enzyme-gated mesoporous silica nanoparticles.

A new gated nanodevice design able to control cargo delivery using glucose as a trigger and cyclodextrin-modified glucose oxidase as a capping agent is reported.

Bioresponsive Mesoporous Silica Nanoparticles for Triggered Drug Release

Mesoporous silica nanoparticles (MSNPs) have garnered a great deal of attention as potential carriers for therapeutic payloads. However, achieving triggered drug release from MSNPs in vivo has been challenging. Here, we describe the synthesis of stimulus-responsive polymer-coated MSNPs and the loading of therapeutics into both the core and shell domains. We characterize MSNP drug-eluting proper...

Antitumoral drug amidase-responsive controlled release on intracellular media using gluconamide-capped mesoporous silica nanoparticles

Dual Enzyme-Triggered Controlled Release on Capped Nanometric Silica Mesoporous Supports

The development of nanoscopic hybrid materials equipped with “molecular gates” showing the ability of releasing target entrapped guests upon the application of an external trigger has attracted great attention and has been extensively explored during recent years. These nanodevices are composed of two subunits, namely, a suitable support and certain capping entities grafted on the surface of th...